TERASTEM Creme

Premium Stem Cell Conditioned Media by MIZUHASHIHOJYUDO. This is a highest-grade stem cell conditioned media developed with pride by MIZUHASHIHOJYUDO. Human stem cells naturally release proteins known as cytokines (growth factors), which support cell activation, growth, and regeneration. These cytokines help restore damaged tissues and maintain healthy cellular function. Human stem cell conditioned media is obtained by culturing stem cells, followed by centrifugation and sterilization to collect the purified supernatant. This supernatant contains hundreds of types of cytokines and is expected to support cellular revitalization and overall skin and wellness care. Because even high-quality conditioned media cannot deliver results if it remains only on the skin surface, the TERASTEM serum adopts a proprietary penetration technology. This confidential delivery system enables beneficial ingredients to penetrate quickly into the skin (stratum corneum) and remain there, helping extend and stabilize their effects. The serum has a refined, smooth texture that absorbs quickly with massage, leaving the skin fresh and deeply hydrated without stickiness. The TERASTEM cream encapsulates cytokine-rich stem cell conditioned media into nano-capsules smaller than intercellular gaps in the stratum corneum, enabling deeper delivery. The active factors are gradually released within the skin, helping maintain firmness, elasticity, and a plump appearance. This advanced regenerative skincare cream supports skin renewal while maintaining clarity and resilience, incorporating the latest biotechnology approaches into daily skincare. The TERASTEM series is available in two product types: a serum and a cream. Features; Quality In medical cell culture, the release of harmful byproducts such as ammonia during stem cell cultivation is not always sufficiently addressed. As a result, some commercially available conditioned media may contain significant levels of impurities — in some cases up to 80%. Many cosmetic products claim to be “stem cell cosmetics” despite containing only minimal amounts of conditioned media, which does not meet true quality standards. MIZUHASHIHOJYUDO sourced samples from multiple culture manufacturers and conducted blind third-party testing to compare growth factor levels and impurities. Based on repeated verification, they selected highly purified and concentrated conditioned media produced by TERASTEM. This material is developed by a biotech venture with extensive medical cell culture experience and uses proprietary purification technology to maximize active factors while minimizing impurities. Concentration Stem cell conditioned media is effective only when formulated at sufficient concentration. Each product’s inclusion level is strictly monitored and validated to ensure performance you can truly feel. High-concentration conditioned media is costly, and advanced delivery technology is required to enhance skin penetration. By simplifying packaging and minimizing advertising expenses, MIZUHASHIHOJYUDO maintains reasonable pricing while preserving high ingredient quality. Penetration Technology MIZUHASHIHOJYUDO’s proprietary penetration technology is applied to both serums and creams to ensure that stem cell conditioned media components effectively reach the stratum corneum. This maximizes the performance of growth factors and active ingredients for efficient skin support. Through strict control of quality, concentration, and delivery technology, these stem cell skincare products are designed to be safe, effective, and highly absorbable — supporting true anti-aging and skin repair care. How to take: After the serum, take an appropriate amount and gently apply it to the skin until absorbed.